Tuesday, April 7, 2009

Isotonic Dextrose Saline


Brand Name given by Opso Saline is IDS
Isotonic Dextrose Saline are ideal for the replacement of Insensible fluid loss, as insensible fluid losses comprises by water loss and a very minimum of electrolyte loss -

What is Insensible fluid loss?

- Fluid loss that is not readily measured and consists mostly of water lost via evaporation through the
skin (two thirds) and respiratory tract (one third).


- Insensible fluid loss also depends on the postnatal age. Because skin thickness intensifies with the age,
the Insensible fluid loss decreases as premature neonates mature.


- Insensible fluid loss ventilated infants receive humidified gas. Therefore, Insensible fluid loss from the
lungs is eliminated in these infants.


IDS are also effective in case of sensible fluid loss -

What is Sensible fluid loss?

- Fluid loss that is measurable and consists of water & electrolyte lost via urine, stool (eg, diarrhea and
Cholera etc.), nasogastric or orogastric drainage and cerebrospinal fluid (eg, ventricular drainage)

Ref: PMD, OSL, Bangladesh

Monday, February 9, 2009

GLOBAL HEAVY CHEMICALS LTD IN BANGLADESH

Global Heavy Chemicals Ltd (GHCL) is the largest manufacturer and supplier of Chlorine, Caustic Soda, Hydrochloric Acid, Sodium Hypochlorite, Bleaching Powder, Chlorinated Paraffin Wax (CPW) and other related products in Bangladesh. GHCL a sister concern of OPSONIN GROUP is located at Hasnabad, Keranigonj, Dhaka. Within this Group OPSO SALINE Ltd was established in 1987 in Barisal, which is using the latest state of the art BFS (Blow Fill & seal) technology of Switzerland. Till now, Opso Saline Ltd is the largest manufacturer of IV Fluids/Antibiotics, Ophthalmic/Otic/Nasal Drops & Ointment and Medical Equipments (Disposable Syringe, Infusion Set, Butterfly Needle etc.) in Bangladesh. Another SBU of this group is Global Capsules Ltd (GCL) established at Rupatoli, Barisal is the manufacturer of Gelatin, empty hard gelatin capsule (EHGC) & Dicalcium Phosphate (DCP).

Clotech is a popular chemical disinfectant made of 5.25% Sodium Hypochlorite (NaOCl) and combined with DM water for enhanced stability. Clotech is often used to clean if they have no metal parts and to disinfect and decontaminate water lines. Clotech is also used in Food processing Plants, Dairies & poultry plants, Laundry, Textiles, Clinic, Hospital and other Health Institutions. Clotech is available in 2 liter, 4liter plastic container in the market. Clotech plays a vital role during flood & cyclone in Bangladesh ensuring safe drinking water.

Products of GHCL are important components in the manufacture of a variety of products that we all rely on as part of our modern way of life. In fact, each time we read a newspaper, use bleach in our laundry, ride in a car, enjoy safe drinking water or take drugs to relieve from disease. Populations of the country are being benefited from one or more of our products.

Chlorine is used as “building blocks” in more than 85% of all pharmaceutical products, 95% of all crop protection chemicals, 60% other commercial chemicals. They are also used in manufacturing of other industrial products.

The crucial balancing factor for putting any Chlore-Alkali industry in Bangladesh is to make avenue to consume Chlorine safely unless all these efforts will go in vein.

ACTIVITIES OF OPSO SALINE GROUP IN BANGLADESH

Industry Overview

Global Heavy Chemicals Limited is located on the southern part of Dhaka district in Hasnabad union under Keranigonj Thana on the south bank of the river Buriganga. Keeping the industrial heritage of Keraniganj in mind, GHCL has set-up its production unit on a 10.5 acars of land. In this project a few blocks has been designed by the consultant engineers based on maximum assurance of safety & utilization of space. Around all the sections there are sufficient space and connecting roads for free movement of vehicles & personnel. The main units of this industry are-

ž Front office area including main gate, security house, guesthouse, weighing bridge & parking area.
ž Administrative building including office block, canteen, workshop etc.
ž 10 MW Power plant including Diesel Generator & Boiler House.
ž 1800 MT water storage tank including two-pump house & cooling tower.
ž Bi-polar membrane cell house including rectifier, rectifier transformer, DCS control room, anolyte & catholyte tank, de-chlorination building as well as quality control department.
ž Utility building including DM plant, Nitrogen plant, Absorption chillers & compressors. This block has got HCl synthesis building including storage tank and delivery platform.
ž Primary & Secondary brine purification area including Salt Saturator, Reactor, Chemical-Dosing tanks, Main Clarifier, Anthracite Filter, Candle Filter, Polished Brine Tank, Ion-Exchange Resin Column and Purified Brine Storage Tank.
ž Automatic Salt washer unit, including separate storage area for raw & washed salt, conveyers, small clarifier etc.
ž Chlorine Drying & Compression building including Bottling area as well as four large storage tank and delivery platform.
ž Caustic Evaporation and Flaking building including bagging and storage facility
ž Hydrogen gas compression and Bottling building
ž Automatic Effluent treatment plant for industrial water treatment

Every individual of Global Heavy Chemicals Ltd. will feel utmost satisfaction to be associated with the development process of other industries by rendering our humble service and high quality products.


Ref: PMD, OSL, Bangladesh

WORLD CHEMICAL PRODUCTS & GLOBAL HEAVY CHEMICALS LTD.

Global Heavy Chemicals Ltd., (GHCL) was incorporated on the 19th of September 2000. In the beginning of 21st Century, GHCL starts its journey as the first private sector Chlore-Alkali Industry in Bangladesh. Significantly related to all the hopes and expectations of the new century, GHCL has energized the vision to open new horizon for industrial development in the country. Integrating the visionary imagination for basic industrial development in this country by our Founder Chairman Late Abdul Khaleque Khan, the successors have already established a number of innovative & import substitute industrial unit mainly in the pharmaceuticals and related sectors.

Chlorine is one of just 20 or so elements that make up all living things. Chlorine and chlorine-related chemicals as disinfectants and pharmaceuticals have saved more lives than any other chemical in the history of human kind. Of the 112 elements that make up the world we live in, 99 percent of the Earth's crust, atmosphere and oceans are comprised of just 12 elements by weight. They are oxygen, silicon, aluminum, iron, calcium, sodium, potassium, magnesium, hydrogen, phosphorous, carbon, and chlorine. In fact, chlorine accounts for more than two percent by weight of all seawater alone.

Chlorine-purified water hailed as one of LIFE’S top achievements of the millennium. Along with the discovery of gravity, printing and landing on the moon, the use of chlorine-purified water was recently named as one of the millennium’s greatest historical events by “LIFE” magazine.

Chlorine has an unusual ability to bind to other elements and compounds to form new matter. Chlorine's outer shell is missing one electron, which makes it highly attractive to other atoms and electrons. This is why chlorine is so useful in producing many man-made products, from thousands of consumer goods to pharmaceuticals and other industrial products.

Ref: PMD, OSL, Bangladesh

Monday, February 2, 2009

Dextrose 10% Injection
Source of water & energy



Dextrose is one of the heat origin for human body, 16.7 kJ heat can be produced from one gram dextrose. So dextrose is usually be used for the supplement of heat and treatment of hypoglycaemia. Fast intravenously administered of Dextrose 10% injection can make tissue dehydrate, so the product can be used as dehydrating agent. Moreover, dextrose is main material, which can maintain and adjust osmotic pressure of peritoneum dialysate.
Dextrose administered by IV route usually enters the blood circulation directly. It is oxidized completely to produce CO2 and H2O and excreted by lung and kidney, accompanied with the production of heat. Available capacity of common people for dextrose is about 6mg/kg/minute. 10% DA is used for supplement of energy and body liquid, for the scarcity of feeding and body liquid caused by all cases i.e. intravenous hyperalimentation, ketosis etc.


Ref: PMD, OSL, Bangladesh

Saturday, January 31, 2009

THE NOSE & IT'S COMMON DISORDER

The Nose is a special sense organ for smell and respiration. This smell is supplied by the olfactory nerve. The olfactory nerve fibres originate from the special olfactory cell on the roof of nose. The olfactory nerves carry impulses of the smell to the olfactory area of the temporal lobes of the brain where sensation and impulses are interpreted and give smell.

Common Functions:
  • Air is cooled down and is made moist
  • The odor of the inspired air can be easily taken
  • The dust particles and bacteria are caught up and removed


Common disease of the Nose

Rhinitis: It is an inflammation of the mucous membranes of the nose with symptoms of sneezing, itching, nasal discharge and congestion. It can be allergic, non-allergic, or both.

Seasonal allergic rhinitis: It is caused by substances that trigger allergies, called allergens.

Perennial allergic rhinitis: It is an IgE-mediated reaction to allergens that show little or now seasonal variation. It is persistent, chronic and generally less severe than seasonal allergic rhinitis.

Ref: PMD,OSL,Bangladesh

Thursday, January 29, 2009

Common disorders of the Endocrine System
are-
1) Hyperthyroidism
2) Hypothyroidism
3) Hyperparathyroidism
4) Hypoparathyroidism
5) Diabetes mellitus
6) Acromegaly
7) Diabetes insipidus

Hyperthyroidism is a condition caused by an overactive thyroid gland. The gland makes too much T4 and T3 hormones. Hormones are substances that affect and control many important functions in the body. Weight loss, Increased appetite, Restlessness, Heat intolerance, Fatgue & Nervousness are the common symptoms of Hyperthyroidism.

Hypothyroidism is a condition in which the thyroid gland fails to produce enough thyroid hormone. Weakness Fatigue Cold intolerance Constipation Weight gain Depression Joint or muscle pain Thin and brittle hair are the common symptoms of Hypothyroidism.

Diabetes mellitus is a condition in which the pancreas no longer produces enough insulin or when cells stop responding to the insulin that is produced, so that glucose in the blood cannot be absorbed into the cells of the body. Symptoms include frequent urination, lethargy, excessive thirst, and hunger. Diabetes mellitus is a chronic disease that causes serious health complications including renal failure, heart disease, stroke, and blindness. The treatment includes changes in diet, oral medications, and in some cases, daily injections of insulin.

Acromegaly is a hormonal disorder that results when the pituitary gland produces excess growth hormone. Most commonly it is a benign GH producing tumor derived from a distinct type of cells and called pituitary adenoma. Acromegaly most commonly affects middle-aged adults and can result in serious illness and premature death. Because of its insidious pathogenesis and slow progression, the disease is hard to diagnose in the early stages and is frequently missed for many years.

Diabetes insipidus (DI) is caused by the inability of the kidneys to conserve water, which leads to frequent urination and pronounced thirst. The amount of water conserved is controlled by antidiuretic hormone, also called Vasopressin.

Ref: PMD, OSL, Bangladesh

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